We are happy to inform that we have managed to finalize publications of some of projects we worked recently. Among those:
VEGF-A Regulates Cellular Localization of SR-BI as Well as Transendothelial Transport of HDL but Not LDL, Velagapudi V et al., Arteriosclerosis, Thrombosis, and Vascular Biology, 2017.
In this work we contributed with siRNA-based High Content Screen analysis. We established an image processing protocol allowing us to characterize HDL / LDL trafficking in high throughput data. Based on these characteristics and statistical analysis we selected a list of potential candidate proteins affecting the trafficking process. Some predictions were right, allowing us to characterize novel agents affecting HDL trafficking.
Hypoxia Induces a HIF-1-Dependent Transition from Collective-to-Amoeboid Dissemination in Epithelial Cancer Cells, Lehmann S et al., Current Biology, 2017.
In this work we contributed with a protocol dedicated to image analysis of Digital Pathology data. Based on the proposed analysis and tools it was possible to quantitatively describe the behaviour of specific cells under hypoxia conditions.
Robust Long-Term Individual Cell Tracking from Brightfield Microscopy Images of Budding Yeast, Versari C and Stoma S et al., Journal of Royal Society Interface, 2017
In this we propose a new method to segment and track budding yeast in brightfield images. The method is available for MATLAB and CellProfiler. Now we focus on making it more accessible for ScopeM users.